Hereditary Cancer Risk.
Screens established predisposition genes — including BRCA1 and BRCA2 and other genes associated with breast, ovarian, colorectal and related cancers. One cheek swab, collected at home and run in our own CLIA-certified laboratory.
- One collection · yours for life
- Reviewed by our lab director
- No appointment, no insurance claim
Panel
Hereditary cancer genes
Sample
Cheek swab at home
Review
Reviewed by our lab director
Price
From $950
What it screens for
The genes oncology guidelines are built around.
This panel looks at inherited variants, not current health. A result changes the screening and prevention conversation with your healthcare provider — it does not diagnose cancer.
BRCA1 and BRCA2
The best-known hereditary cancer genes, associated with breast, ovarian and related cancers — and with screening and prevention options when identified early.
Colorectal cancer genes
Genes associated with Lynch syndrome and other inherited colorectal cancer predispositions, where colonoscopy schedules change based on a result.
Other established predisposition genes
Established genes associated with pancreatic, prostate, melanoma, endometrial and other cancers covered by professional guidelines.
Who this is for
About 1 in 10 cancers is linked to an inherited change that runs in families.
Cancer that runs in the family
Multiple relatives with the same or related cancers, especially when diagnosed young.
A young diagnosis in the family
A relative diagnosed before standard screening ages is the most common trigger for testing.
No family history, no baseline
Adoption or incomplete records leave a blank that testing fills.
Is this panel right for you?
Cancer runs in your family, especially at younger ages.
More than one relative has had the same or related cancers.
A relative has a known hereditary cancer variant.
You are planning a family and want to know what you carry.
Your doctor or a genetic counselor suggested testing.
You want results you can keep for life.
Answering yes to even one of these is a good reason to test now rather than after a diagnosis.
Before you order
Total price
From $950
One-time price, shown in full at checkout. No separate fee for the kit, return shipping or the healthcare provider order.
What's included
Kit to report
Cheek-swab kit with instructions, a prepaid FedEx overnight return label, the healthcare provider order, testing in our CLIA-certified lab and a report in your secure portal.
Who orders the test
A licensed healthcare provider
A licensed healthcare provider in our network reviews your request and places the order during checkout, at no extra cost. No referral needed.
Genetic counseling
Available
Genetic counseling is available with every panel, and we recommend reviewing hereditary cancer findings with a genetic counselor or your healthcare provider.
The science
What the evidence says about getting tested.
Roughly one cancer in ten is linked to an inherited variant — and the genes responsible are no longer research topics. BRCA1, BRCA2 and the Lynch syndrome genes sit at the center of professional screening guidelines, because a confirmed inherited risk changes colonoscopy schedules, imaging start ages and prevention options long before any diagnosis. Identifying the variant is the step that makes surveillance personal instead of average.
5–10%
of all cancers are linked to an inherited variant that can be identified by testing.
Source: National Cancer Institute
≈70%
lifetime breast-cancer risk associated with a BRCA1 pathogenic variant, versus about 13% average risk.
Source: NCI BRCA fact sheet
≈50%
lifetime breast-cancer risk with a BRCA2 pathogenic variant (about 45–69%), compared with ~13% average.
Source: NCI BRCA fact sheet
1 in 279
people carry a Lynch syndrome variant, the most common inherited colorectal cancer predisposition.
Source: Lynch syndrome prevalence studies
How often should you test?
Test once — inherited variants don't change. The highest-value moments are when cancer appears repeatedly or early in the family, when a relative has a known hereditary variant, and before family-planning conversations about what you might pass on.
References
- National Cancer Institute — BRCA gene mutations: cancer risk fact sheet.
- National Cancer Institute — Cancer genetics overview (hereditary cancer and inherited risk).
- MedlinePlus Genetics — Lynch syndrome: prevalence, inheritance and colorectal cancer risk.
- PubMed literature — population prevalence of Lynch syndrome (about 1 in 279).
Questions people actually ask
Know your risks while you can act on them.
One collection, one report, and a screening conversation with your healthcare provider that starts from something real.