Cardiovascular Risk.
Screens for inherited variants associated with conditions such as familial hypercholesterolemia and inherited cardiomyopathies — the kinds of risk that can be managed well when identified early. One cheek swab, collected at home and run in our own CLIA-certified laboratory.
- One collection · yours for life
- Reviewed by our lab director
- No appointment, no insurance claim
Panel
Inherited cardiovascular variants
Sample
Cheek swab at home
Review
Reviewed by our lab director
Price
From $950
What it screens for
The risks that run silently in families.
This panel looks at inherited variants, not current health. A result changes the screening and prevention conversation with your healthcare provider — it does not diagnose a condition.
Familial hypercholesterolemia
Inherited variants that raise lifetime cholesterol levels — one of the most treatable inherited risks when identified early.
Inherited cardiomyopathies
Variants associated with heart-muscle conditions, where family screening and imaging schedules can change based on a result.
Rhythm and vascular risk
Variants associated with inherited arrhythmias and vascular conditions that benefit from earlier surveillance.
Antiplatelet metabolism
Metabolizer status that may affect whether a standard dose of a medication such as clopidogrel has the intended effect.
Who this is for
A single sample, and the result stays valid for the rest of your life.
Heart disease that runs in the family
Early heart attacks, high cholesterol across generations or a relative's unexplained sudden death.
A relative diagnosed young
Diagnosis before 55 in men or 65 in women raises the likelihood of an inherited component.
No family history, no baseline
Adoption or incomplete records leave a blank that testing fills.
Is this panel right for you?
Heart disease or stroke runs in your family.
A relative was diagnosed young, or more than one relative was affected.
You have been told your cholesterol is high despite a healthy lifestyle.
You want screening timed to your actual risk, not just your age.
Your doctor or a genetic counselor suggested testing.
You want results you can keep for life.
Answering yes to even one of these is a good reason to test now rather than after a diagnosis.
Before you order
Total price
From $950
One-time price, shown in full at checkout. No separate fee for the kit, return shipping or the healthcare provider order.
What's included
Kit to report
Cheek-swab kit with instructions, a prepaid FedEx overnight return label, the healthcare provider order, testing in our CLIA-certified lab and a report in your secure portal.
Who orders the test
A licensed healthcare provider
A licensed healthcare provider in our network reviews your request and places the order during checkout, at no extra cost. No referral needed.
Genetic counseling
Available
Genetic counseling is available with every panel, and we recommend reviewing cardiovascular findings with a genetic counselor or your healthcare provider.
The science
What the evidence says about getting tested.
Inherited cardiovascular risk is common and largely silent until it matters. Familial hypercholesterolemia affects roughly 1 in 250 people and most carriers don't know it — yet it is one of the most treatable inherited conditions when identified early. Inherited cardiomyopathies and arrhythmias follow the same pattern: a variant found today can change screening, imaging and prevention for you and your relatives for decades.
1 in 250
people have familial hypercholesterolemia, the most common inherited cardiovascular condition.
Source: MedlinePlus Genetics
≈80%
of people with familial hypercholesterolemia are undiagnosed — the reason family-based testing matters.
Source: European Heart Journal, 2013
About 1 in 500
people have hypertrophic cardiomyopathy, the most common inherited heart-muscle condition.
Source: Cardiology genetics reviews
About half
of first heart attacks occur without prior warning symptoms — inherited risk moves screening earlier.
Source: American Heart Association
How often should you test?
Test once — inherited variants don't change. The highest-value moments are when early heart disease, very high cholesterol or unexplained sudden death appear in the family, before family screening decisions are made, and when your own cholesterol runs high despite a healthy lifestyle.
References
- MedlinePlus Genetics — Familial hypercholesterolemia: inheritance, prevalence and cardiovascular risk.
- PubMed literature — familial hypercholesterolaemia is underdiagnosed and undertreated in the general population (Nordestgaard et al., European Heart Journal).
- PubMed literature — prevalence and genetics of hypertrophic cardiomyopathy.
Questions people actually ask
Know your risks while you can act on them.
One collection, one report, and a screening conversation with your healthcare provider that starts from something real.